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Filtered Search Results
Cayman Chemical Vitellogenin sea bream Poly
A form of the sugar Neu5Ac O-linked with the nucleotide CMP serves as the substrate for sialyltransferases which transfer Neu5Ac from CMP-sialic acid to various acceptor substrates most commonly at terminal positions of the oligosaccharide component of glycoproteins or glycolipids
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Cayman Chemical Afatinib (maleate), Purity: ≥95%, CAS: 850140-73-7, 500 mg
An inhibitor of EGFR and ErbB2 (IC50s = 0.5 and 14 nM, respectively); increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein; reduces tumor growth in ErbB2-amplified NCI-N87 and NUGC4 gastric cancer mouse xenograft models at 20 mg/kg
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Cayman Chemical Vilazodone (hydrochloride), Purity: ≥95%, CAS: 163521-08-2, 250 mg
An SSRI and a partial agonist of 5-HT1A (IC50 s = 0.2 and 0.5 nM, respectively); increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex at 1 and 3 mg/kg, i.p.; decreases immobility in the forced swim test in both rats and mice at 1 mg/kg
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Cayman Chemical Ricinelaidic Acid, Purity: ≥95%, CAS: 540-12-5, 250 mg
An LTB4 receptor antagonist (Ki = 2 µM); inhibits chemotaxis and calcium flux by LTB4 in isolated human neutrophils (IC50s = 10 and 7 µM, respectively); inhibits bronchoconstriction induced by LTB4 in rats by 46%
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Cayman Chemical Alosetron (hydrochloride), Purity: ≥98%, CAS: 122852-69-1, 250 mg
A 5-HT3 receptor antagonist (Kis = 0.3 and 0.4 nM for the rat cortical and human recombinant receptors, respectively); selective for 5-HT3 over 5-HT2 and 5-HT1A receptors (Kis = 6.3 and >100 µM, respectively), as well as α1-, β1-, and β2- adrenergic, M1, M2, and M3 muscarinic, GABAA, dopamine D2, and nicotinic receptors at 10 μM; inhibits 5-HT-induced depolarization of isolated rat vagus nerve at 0.3-10 nM; reduces wrap restraint stress-induced defecation and the number of abdominal muscle contractions in a rat model of IBS-D at 0.1 mg/kg
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Revvity Health Sciences Inc Anti-Rabbit IgG (Goat), Biotin-Labeled, 0.5mg Lyophilized
Anti-Rabbit IgG (Goat), Biotin-Labeled, 0.5mg Lyophilized
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Cayman Chemical (–)-Lobelin (hydrochloride), Purity: ≥95%, CAS: 134-63-4, 250 mg
An alkaloid with diverse biological activities; binds to nAChRs in rat brain homogenates (Ki = 4 nM); has antinociceptive effects in the tail-flick assay in mice; reduces the number of errors in a repeated acquisition procedure in the radial arm maze in rats at 0.3 and 0.9 mg/kg; decreases immobility time in the forced swim test and feeding latency in the novelty suppressed feeding test at 1 and 4 mg/kg
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Cayman Chemical GoatntIChIckenIgYSureLIg1ea
Goat Anti-Chicken IgY conjugated to SureLight™ R-PE, 100UG Antibody: Goat polyclonal Anti-Chicken IgY Isotype: IgY Uses: Flow cytometry, fluorescence-activated cell sorting, and protein microarrays
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Cayman Chemical Tiamulin (fumarate), Purity: ≥95%, CAS: 55297-96-6, 1 g
A pleuromutilin antibiotic; active against various mycobacteria (MICs = 0.0025-0.25 µg/ml) and various Gram-positive bacteria, including MRSA; binds to the peptidyl transferase in the 50S ribosomal subunit to inhibit protein synthesis
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Cayman Chemical 2,3-Butanedione-2-monoxime, Purity: ≥95%, CAS: 57-71-6, 25 g
A non-selective, reversible myosin ATPase inhibitor with phosphatase-like properties; inhibits L-type Ca2+ channels
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Cayman Chemical [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - Pancreatic Polypeptide (human) (acetate), Purity: ≥98%, 5 mg
An agonist of NPY receptor Y5; inhibits forskolin-induced cAMP production in HEK293 cells expressing the Y5 receptor (EC50 = 17 nM); selectively binds to Y5 (IC50 = 0.24 nM in HEK293 cells expressing the human receptor) over Y1, Y2, and Y4 (IC50s = 530, >500, and 51 nM, respectively, in BHK-21 cells expressing the human receptors); increases VEGF levels, as well as endothelial branch length and branch points, in 4T1 cells in a concentration-dependent manner; induces relaxation of vasopressin-precontracted rat mesenteric arteries at 1 µM; increases food intake in rats at 0.2 and 2 nmol/animal, i.c.v.
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Cayman Chemical paramethoxyButyryl fentnyl
An internal standard for the quantification of para-methoxy-butyryl fentanyl by GC- or LC-MS; regulated as a Schedule I compound in the United States; intended for research and forensic applications
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Cayman Chemical 2-Aminotetralin, Purity: ≥95%, CAS: 2954-50-9, 500 mg
A neuromodulatory agent; inhibits 5-HT and norepinephrine reuptake in rat brain at 39.4 mg/kg; induces hypothermia when administered by intracisternal or intraperitoneal injection; induces hyperthermia when implanted as crystals in the medial preoptic area of the hypothalamus in rats; substitutes for (+)-amphetamine in rats in a two-lever drug discrimination test in a dose-dependent manner
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Cayman Chemical Mizolastine, Purity: ≥98%, CAS: 108612-45-9, 250 mg
A histamine H1 receptor antagonist (Ki = 0.001 µM); selective for histamine H1 over histamine H2 and H3 receptors (Kis = >100 µM for both), as well as 5-HT1A , 5-HT1B, 5-HT1C, 5-HT1D, 5-HT2, and 5-HT3, dopamine D1 and D2, α1- and α2-adrenergic, adenosine, and muscarinic receptors in radioligand binding assays (Kis = >1 µM for all); reduces histamine release from bronchial mast cells in ovalbumin-sensitized guinea pigs at 0.1, 0.3, and 1 mg/kg; reduces histamine-induced paw edema in rats, skin edema in dogs, and bronchoconstriction in guinea pigs (ED50s = 0.5, 0.07, and 0.03 mg/kg, respectively); inhibits passive cutaneous anaphylaxis, as well as compound 48/80-induced lethal shock in rats (ED50s = 1.6 and 0.07 mg/kg, respectively)
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Cayman Chemical THUNDRPhosphoeIF4S209 4800Wel
Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-eIF4E (S209) in cell lysates
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